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Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives

As our global population ages, the treatment of neurodegenerative diseases is critical to our society. In recent years, researchers have begun to study the role of biologically active chemicals from plants and herbs to gain new inspiration and develop new therapeutic drugs. Ginseng (Panax ginseng C....

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Autores principales: Huang, Xing, Li, Ning, Pu, Yiqiong, Zhang, Tong, Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720911/
https://www.ncbi.nlm.nih.gov/pubmed/31416121
http://dx.doi.org/10.3390/molecules24162939
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author Huang, Xing
Li, Ning
Pu, Yiqiong
Zhang, Tong
Wang, Bing
author_facet Huang, Xing
Li, Ning
Pu, Yiqiong
Zhang, Tong
Wang, Bing
author_sort Huang, Xing
collection PubMed
description As our global population ages, the treatment of neurodegenerative diseases is critical to our society. In recent years, researchers have begun to study the role of biologically active chemicals from plants and herbs to gain new inspiration and develop new therapeutic drugs. Ginseng (Panax ginseng C.A. Mey.) is a famous Chinese herbal medicine with a variety of pharmacological activities. It has been used to treat various diseases since ancient times. Extensive research over the years has shown that ginseng has potential as a neuroprotective drug, and its neuroprotective effects can be used to treat and prevent neurological damage or pathologically related diseases (such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, depression symptoms, and strokes). Moreover, evidence for the medicinal and health benefits of ginsenoside, its main active ingredient, in the prevention of neurodegenerative diseases is increasing, and current clinical results have not reported any serious adverse reactions to ginseng. Therefore, we briefly review the recent research and development on the beneficial effects and mechanisms of ginseng and its main active ingredient, ginsenoside, in the prevention and treatment of neurodegenerative diseases, hoping to provide some ideas for the discovery and identification of ginseng neuroprotection.
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spelling pubmed-67209112019-09-10 Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives Huang, Xing Li, Ning Pu, Yiqiong Zhang, Tong Wang, Bing Molecules Review As our global population ages, the treatment of neurodegenerative diseases is critical to our society. In recent years, researchers have begun to study the role of biologically active chemicals from plants and herbs to gain new inspiration and develop new therapeutic drugs. Ginseng (Panax ginseng C.A. Mey.) is a famous Chinese herbal medicine with a variety of pharmacological activities. It has been used to treat various diseases since ancient times. Extensive research over the years has shown that ginseng has potential as a neuroprotective drug, and its neuroprotective effects can be used to treat and prevent neurological damage or pathologically related diseases (such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, depression symptoms, and strokes). Moreover, evidence for the medicinal and health benefits of ginsenoside, its main active ingredient, in the prevention of neurodegenerative diseases is increasing, and current clinical results have not reported any serious adverse reactions to ginseng. Therefore, we briefly review the recent research and development on the beneficial effects and mechanisms of ginseng and its main active ingredient, ginsenoside, in the prevention and treatment of neurodegenerative diseases, hoping to provide some ideas for the discovery and identification of ginseng neuroprotection. MDPI 2019-08-14 /pmc/articles/PMC6720911/ /pubmed/31416121 http://dx.doi.org/10.3390/molecules24162939 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Huang, Xing
Li, Ning
Pu, Yiqiong
Zhang, Tong
Wang, Bing
Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
title Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
title_full Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
title_fullStr Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
title_full_unstemmed Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
title_short Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
title_sort neuroprotective effects of ginseng phytochemicals: recent perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720911/
https://www.ncbi.nlm.nih.gov/pubmed/31416121
http://dx.doi.org/10.3390/molecules24162939
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