Identification of New Inhibitors with Potential Antitumor Activity from Polypeptide Structures via Hierarchical Virtual Screening

Leukemias are neoplasms that affect hematopoietic cells, which are developed by genetic alterations (mutations) that lead to the loss of proliferation control mechanisms (maturation and/or cell death). The α4β1 integrin receptor is a therapeutic target for inflammation, autoimmune diseases and lymph...

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Detalles Bibliográficos
Autores principales: Ferreira, Elenilze F. B., Silva, Luciane B., Costa, Glauber V., Costa, Josivan S., Fujishima, Mayara A. T., Leão, Rozires P., Ferreira, André L. S., Federico, Leonardo B., Silva, Carlos H. T. P., Rosa, Joaquín M. C., Macêdo, Williams J. C., Santos, Cleydson B. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720962/
https://www.ncbi.nlm.nih.gov/pubmed/31416180
http://dx.doi.org/10.3390/molecules24162943

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