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Synthesis, Characterization and Antioxidant Properties of a New Lipophilic Derivative of Edaravone
As part of a program aimed to obtain antioxidants able to interact with cell membrane, edaravone (EdV, 3-methyl-1-phenyl-2-pyrazolin-5-one), a well-known free radical scavenger, has been modified by alkylation at its allylic position (4) with a C-18 hydrocarbon chain, and the increased lipophilicity...
Autores principales: | Minnelli, Cristina, Laudadio, Emiliano, Galeazzi, Roberta, Rusciano, Dario, Armeni, Tatiana, Stipa, Pierluigi, Cantarini, Mattia, Mobbili, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720979/ https://www.ncbi.nlm.nih.gov/pubmed/31370225 http://dx.doi.org/10.3390/antiox8080258 |
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