Cargando…

Towards Mechanism-Based Treatments for Fragile X Syndrome

Detalles Bibliográficos
Autores principales:	Kumari, Daman, Gazy, Inbal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Editorial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721292/ https://www.ncbi.nlm.nih.gov/pubmed/31426300 http://dx.doi.org/10.3390/brainsci9080202

Ejemplares similares

Pharmacological Reactivation of the Silenced FMR1 Gene as a Targeted Therapeutic Approach for Fragile X Syndrome
por: Kumari, Daman, et al.
Publicado: (2019)

The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome
por: Kumari, Daman, et al.
Publicado: (2009)

SIRT1 Inhibition Alleviates Gene Silencing in Fragile X Mental Retardation Syndrome
por: Biacsi, Rea, et al.
Publicado: (2008)

Repeat Instability in the Fragile X-Related Disorders: Lessons from a Mouse Model
por: Zhao, Xiaonan, et al.
Publicado: (2019)

A MutSβ-Dependent Contribution of MutSα to Repeat Expansions in Fragile X Premutation Mice?
por: Zhao, Xiao-Nan, et al.
Publicado: (2016)

Repeat-mediated epigenetic dysregulation of the FMR1 gene in the fragile X-related disorders
por: Usdin, Karen, et al.
Publicado: (2015)

Fragile X Syndrome: Recent Research Updates toward Capturing Treatments’ Improvement in Clinical Trials
por: Budimirovic, Dejan B., et al.
Publicado: (2022)

CGG Repeat Expansion, and Elevated Fmr1 Transcription and Mitochondrial Copy Number in a New Fragile X PM Mouse Embryonic Stem Cell Model
por: Gazy, Inbal, et al.
Publicado: (2020)

CGG-repeat dynamics and FMR1 gene silencing in fragile X syndrome stem cells and stem cell-derived neurons
por: Zhou, Yifan, et al.
Publicado: (2016)

Minocycline and MMPs: towards treatment for Fragile X syndrome
Publicado: (2011)

Small Molecules Targeting H3K9 Methylation Prevent Silencing of Reactivated FMR1 Alleles in Fragile X Syndrome Patient Derived Cells
por: Kumari, Daman, et al.
Publicado: (2020)

Fragile X Premutation
por: Tassone, Flora, et al.
Publicado: (2014)

Fragile X syndrome and fragile X-associated disorders
por: Rajaratnam, Akash, et al.
Publicado: (2017)

Editorial for the Fragile X Syndrome Genetics Special Issue: May 2023
por: Godler, David E., et al.
Publicado: (2023)

Repeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disorders
por: Usdin, Karen, et al.
Publicado: (2014)

Targeted treatments for fragile X syndrome
por: Berry-Kravis, Elizabeth, et al.
Publicado: (2011)

Parent and Caregiver Perspectives towards Cannabidiol as a Treatment for Fragile X Syndrome
por: Maertens, Madison, et al.
Publicado: (2022)

Fragile X Syndrome
por: McLennan, Yingratana, et al.
Publicado: (2011)

Fragile X Syndrome
por: Saldarriaga, Wilmar, et al.
Publicado: (2014)

Common Threads: Aphidicolin-Inducible and Folate-Sensitive Fragile Sites in the Human Genome
por: Lokanga, Rachel Adihe, et al.
Publicado: (2021)

New Targeted Treatments for Fragile X Syndrome
por: Protic, Dragana, et al.
Publicado: (2019)

Modifiers of Somatic Repeat Instability in Mouse Models of Friedreich Ataxia and the Fragile X-Related Disorders: Implications for the Mechanism of Somatic Expansion in Huntington’s Disease
por: Zhao, Xiaonan, et al.
Publicado: (2021)

Translation in fragile X: no home runs in the first at-bat
por: Veenstra-VanderWeele, Jeremy
Publicado: (2017)

Progress toward therapeutic potential for AFQ056 in Fragile X syndrome
por: Sourial, Mary, et al.
Publicado: (2013)

Aging in fragile X syndrome
por: Utari, Agustini, et al.
Publicado: (2010)

Fragile X Syndrome in children
por: Acero-Garcés, David O., et al.
Publicado: (2023)

Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome
por: Kelley, Karen, et al.
Publicado: (2012)

Mechanisms Driving the Emergence of Neuronal Hyperexcitability in Fragile X Syndrome
por: Bülow, Pernille, et al.
Publicado: (2022)

Metformin treatment in young children with fragile X syndrome
por: Biag, Hazel Maridith B., et al.
Publicado: (2019)

Systematic review of pharmacological treatments in fragile X syndrome
por: Rueda, Jose-Ramon, et al.
Publicado: (2009)

Modulation of the GABAergic pathway for the treatment of fragile X syndrome
por: Lozano, Reymundo, et al.
Publicado: (2014)

Emerging pharmacologic treatment options for fragile X syndrome
por: Schaefer, Tori L, et al.
Publicado: (2015)

Fragile X Syndrome: Prevalence, Treatment, and Prevention in China
por: Niu, Manman, et al.
Publicado: (2017)

Best Practices in Fragile X Syndrome Treatment Development
por: Erickson, Craig A., et al.
Publicado: (2018)

Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome
por: Berman, Robert F, et al.
Publicado: (2014)

EXPLAIN Fragile-X: an explorative, longitudinal study on the characterization, treatment pathways, and patient-related outcomes of Fragile X Syndrome
por: Haessler, Frank, et al.
Publicado: (2013)

Molecular Biomarkers in Fragile X Syndrome
por: Zafarullah, Marwa, et al.
Publicado: (2019)

Pathological Plasticity in Fragile X Syndrome
por: Martin, Brandon S., et al.
Publicado: (2012)

Auditory Processing in Fragile X Syndrome
por: Rotschafer, Sarah E., et al.
Publicado: (2014)

Modeling Fragile X Syndrome in Drosophila
por: Drozd, Małgorzata, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_l3h3qg3c6tpc96nvtsbvcog44l