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PTEN Tumor-Suppressor: The Dam of Stemness in Cancer

PTEN is one of the most frequently inactivated tumor suppressor genes in cancer. Loss or variation in PTEN gene/protein levels is commonly observed in a broad spectrum of human cancers, while germline PTEN mutations cause inherited syndromes that lead to increased risk of tumors. PTEN restrains tumo...

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Detalles Bibliográficos
Autores principales:	Luongo, Francesca, Colonna, Francesca, Calapà, Federica, Vitale, Sara, Fiori, Micol E., De Maria, Ruggero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721423/ https://www.ncbi.nlm.nih.gov/pubmed/31366089 http://dx.doi.org/10.3390/cancers11081076

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