PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) is the most aggressive type of breast cancer, which shows resistance to common breast cancer therapies, as it lacks the expression of the most common breast cancer targets. Therefore, TNBC treatment remains a challenge. Targeting programmed cell death-ligand 1 (P...

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Detalles Bibliográficos
Autores principales: Saleh, Reem, Taha, Rowaida Z., Sasidharan Nair, Varun, Alajez, Nehad M., Elkord, Eyad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721435/
https://www.ncbi.nlm.nih.gov/pubmed/31349612
http://dx.doi.org/10.3390/cancers11081050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721435/
https://www.ncbi.nlm.nih.gov/pubmed/31349612
http://dx.doi.org/10.3390/cancers11081050

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