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PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer
Triple negative breast cancer (TNBC) is the most aggressive type of breast cancer, which shows resistance to common breast cancer therapies, as it lacks the expression of the most common breast cancer targets. Therefore, TNBC treatment remains a challenge. Targeting programmed cell death-ligand 1 (P...
Autores principales: | Saleh, Reem, Taha, Rowaida Z., Sasidharan Nair, Varun, Alajez, Nehad M., Elkord, Eyad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721435/ https://www.ncbi.nlm.nih.gov/pubmed/31349612 http://dx.doi.org/10.3390/cancers11081050 |
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