Do GNAQ and GNA11 Differentially Affect Inflammation and HLA Expression in Uveal Melanoma?

Inflammation, characterized by high numbers of infiltrating leukocytes and a high HLA Class I expression, is associated with a bad prognosis in uveal melanoma (UM). We wondered whether mutations in GNA11 or GNAQ differentially affect inflammation and HLA expression, and thereby progression of the di...

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Detalles Bibliográficos
Autores principales: van Weeghel, Christiaan, Wierenga, Annemijn P. A., Versluis, Mieke, van Hall, Thorbald, van der Velden, Pieter A., Kroes, Wilma G. M., Pfeffer, Ulrich, Luyten, Gregorius P. M., Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721447/
https://www.ncbi.nlm.nih.gov/pubmed/31394807
http://dx.doi.org/10.3390/cancers11081127

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