Type 1 Sodium Calcium Exchanger Forms a Complex with Carbonic Anhydrase IX and Via Reverse Mode Activity Contributes to pH Control in Hypoxic Tumors

Hypoxia and acidosis are among the key microenvironmental factors that contribute to cancer progression. We have explored a possibility that the type 1Na(+)/Ca(2+) exchanger (NCX1) is involved in pH control in hypoxic tumors. We focused on changes in intracellular pH, co-localization of NCX1, carbon...

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Detalles Bibliográficos
Autores principales: Liskova, Veronika, Hudecova, Sona, Lencesova, Lubomira, Iuliano, Filippo, Sirova, Marta, Ondrias, Karol, Pastorekova, Silvia, Krizanova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721473/
https://www.ncbi.nlm.nih.gov/pubmed/31395807
http://dx.doi.org/10.3390/cancers11081139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721473/
https://www.ncbi.nlm.nih.gov/pubmed/31395807
http://dx.doi.org/10.3390/cancers11081139

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