Interphase Cytogenetic Analysis of Micronucleated and Multinucleated Cells Supports the Premature Chromosome Condensation Hypothesis as the Mechanistic Origin of Chromothripsis

The discovery of chromothripsis in cancer genomes challenges the long-standing concept of carcinogenesis as the result of progressive genetic events. Despite recent advances in describing chromothripsis, its mechanistic origin remains elusive. The prevailing conception is that it arises from a massi...

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Detalles Bibliográficos
Autores principales: Pantelias, Antonio, Karachristou, Ioanna, Georgakilas, Alexandros G., Terzoudi, Georgia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721583/
https://www.ncbi.nlm.nih.gov/pubmed/31390832
http://dx.doi.org/10.3390/cancers11081123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721583/
https://www.ncbi.nlm.nih.gov/pubmed/31390832
http://dx.doi.org/10.3390/cancers11081123

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