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Cholesterol Interaction Directly Enhances Intrinsic Activity of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

The recent cryo-electron microscopy structures of zebrafish and the human cystic fibrosis transmembrane conductance regulator (CFTR) provided unprecedented insights into putative mechanisms underlying gating of its anion channel activity. Interestingly, despite predictions based on channel activity...

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Detalles Bibliográficos
Autores principales:	Chin, Stephanie, Ramjeesingh, Mohabir, Hung, Maurita, Ereño-Oreba, June, Cui, Hong, Laselva, Onofrio, Julien, Jean-Philippe, Bear, Christine E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721619/ https://www.ncbi.nlm.nih.gov/pubmed/31370288 http://dx.doi.org/10.3390/cells8080804

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