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Tailor-Made Detection of Individual Phosphorylated and Non-Phosphorylated EPIYA-Motifs of Helicobacter pylori Oncoprotein CagA
The gastric pathogen and carcinogen Helicobacter pylori (H. pylori) encodes a type IV secretion system for translocation of the effector protein CagA into host cells. Injected CagA becomes tyrosine-phosphorylated at the five amino acid residue Glutamate-Proline- Isoleucine-Tyrosine-Alanine (EPIYA)-s...
Autores principales: | Pachathundikandi, Suneesh Kumar, Gutiérrez-Escobar, Andrés Julián, Tegtmeyer, Nicole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721621/ https://www.ncbi.nlm.nih.gov/pubmed/31412675 http://dx.doi.org/10.3390/cancers11081163 |
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