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Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models

Patient-derived xenograft (PDX) models are created by engraftment of patient tumor tissues into immunocompetent mice. Since a PDX model retains the characteristics of the primary patient tumor including gene expression profiles and drug responses, it has become the most reliable in vivo human cancer...

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Detalles Bibliográficos
Autores principales:	Okada, Seiji, Vaeteewoottacharn, Kulthida, Kariya, Ryusho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721637/ https://www.ncbi.nlm.nih.gov/pubmed/31412684 http://dx.doi.org/10.3390/cells8080889

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