Cargando…

Targeting the CD40-CD154 Signaling Pathway for Treatment of Autoimmune Arthritis

Full activation of T lymphocytes requires signals from both T cell receptors and costimulatory molecules. In addition to CD28, several T cell molecules could deliver costimulatory signals, including CD154, which primarily interacts with CD40 on B-cells. CD40 is a critical molecule regulating several...

Descripción completa

Detalles Bibliográficos
Autores principales: Lai, Jenn-Haung, Luo, Shue-Fen, Ho, Ling-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721639/
https://www.ncbi.nlm.nih.gov/pubmed/31426619
http://dx.doi.org/10.3390/cells8080927