WNT Signaling in Disease

Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the...

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Detalles Bibliográficos
Autores principales: Ng, Li Fang, Kaur, Prameet, Bunnag, Nawat, Suresh, Jahnavi, Sung, Isabelle Chiao Han, Tan, Qian Hui, Gruber, Jan, Tolwinski, Nicholas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721652/
https://www.ncbi.nlm.nih.gov/pubmed/31382613
http://dx.doi.org/10.3390/cells8080826
Descripción
Sumario:Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments.

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