WNT Signaling in Disease

Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the...

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Autores principales: Ng, Li Fang, Kaur, Prameet, Bunnag, Nawat, Suresh, Jahnavi, Sung, Isabelle Chiao Han, Tan, Qian Hui, Gruber, Jan, Tolwinski, Nicholas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721652/
https://www.ncbi.nlm.nih.gov/pubmed/31382613
http://dx.doi.org/10.3390/cells8080826
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author Ng, Li Fang
Kaur, Prameet
Bunnag, Nawat
Suresh, Jahnavi
Sung, Isabelle Chiao Han
Tan, Qian Hui
Gruber, Jan
Tolwinski, Nicholas S.
author_facet Ng, Li Fang
Kaur, Prameet
Bunnag, Nawat
Suresh, Jahnavi
Sung, Isabelle Chiao Han
Tan, Qian Hui
Gruber, Jan
Tolwinski, Nicholas S.
author_sort Ng, Li Fang
collection PubMed
description Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments.
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spelling pubmed-67216522019-09-10 WNT Signaling in Disease Ng, Li Fang Kaur, Prameet Bunnag, Nawat Suresh, Jahnavi Sung, Isabelle Chiao Han Tan, Qian Hui Gruber, Jan Tolwinski, Nicholas S. Cells Review Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments. MDPI 2019-08-03 /pmc/articles/PMC6721652/ /pubmed/31382613 http://dx.doi.org/10.3390/cells8080826 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ng, Li Fang
Kaur, Prameet
Bunnag, Nawat
Suresh, Jahnavi
Sung, Isabelle Chiao Han
Tan, Qian Hui
Gruber, Jan
Tolwinski, Nicholas S.
WNT Signaling in Disease
title WNT Signaling in Disease
title_full WNT Signaling in Disease
title_fullStr WNT Signaling in Disease
title_full_unstemmed WNT Signaling in Disease
title_short WNT Signaling in Disease
title_sort wnt signaling in disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721652/
https://www.ncbi.nlm.nih.gov/pubmed/31382613
http://dx.doi.org/10.3390/cells8080826
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AT sungisabellechiaohan wntsignalingindisease
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