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Absence of Uncoupling Protein-3 at Thermoneutrality Impacts Lipid Handling and Energy Homeostasis in Mice
The role of uncoupling protein-3 (UCP3) in energy and lipid metabolism was investigated. Male wild-type (WT) and UCP3-null (KO) mice that were housed at thermoneutrality (30 °C) were used as the animal model. In KO mice, the ability of skeletal muscle mitochondria to oxidize fatty acids (but not pyr...
Autores principales: | Lombardi, Assunta, Busiello, Rosa Anna, De Matteis, Rita, Lionetti, Lillà, Savarese, Sabrina, Moreno, Maria, Gentile, Alessandra, Silvestri, Elena, Senese, Rosalba, de Lange, Pieter, Cioffi, Federica, Lanni, Antonia, Goglia, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721699/ https://www.ncbi.nlm.nih.gov/pubmed/31426456 http://dx.doi.org/10.3390/cells8080916 |
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