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EGFR/ErbB Inhibition Promotes OPC Maturation up to Axon Engagement by Co-Regulating PIP2 and MBP

Remyelination in the adult brain relies on the reactivation of the Neuronal Precursor Cell (NPC) niche and differentiation into Oligodendrocyte Precursor Cells (OPCs) as well as on OPC maturation into myelinating oligodendrocytes (OLs). These two distinct phases in OL development are defined by tran...

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Detalles Bibliográficos
Autores principales: Nocita, Emanuela, Del Giovane, Alice, Tiberi, Marta, Boccuni, Laura, Fiorelli, Denise, Sposato, Carola, Romano, Elena, Basoli, Francesco, Trombetta, Marcella, Rainer, Alberto, Traversa, Enrico, Ragnini-Wilson, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721729/
https://www.ncbi.nlm.nih.gov/pubmed/31390799
http://dx.doi.org/10.3390/cells8080844