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Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models

As glioblastomas are mostly localized infiltrative lesions, gene therapy based on the retroviral replicating vector (RRV) system is considered an attractive strategy. Combinations of multiple suicide genes can circumvent the limitations associated with each gene, achieving direct and synergistic cyt...

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Detalles Bibliográficos
Autores principales: Lee, Mijeong, Kim, Yeon-Soo, Lee, Kyoungmin, Kang, Moonkyung, Shin, Hyemi, Oh, Jeong-Woo, Koo, Harim, Kim, Donggeon, Kim, Yejin, Kong, Doo-Sik, Nam, Do-Hyun, Lee, Hye Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721803/
https://www.ncbi.nlm.nih.gov/pubmed/31370279
http://dx.doi.org/10.3390/cancers11081090