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DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) has been linked to chronic lung inflammation. Drosha ribonuclease III (DROSHA), a class 2 ribonuclease III enzyme, plays a key role in microRNA (miRNA) biogenesis. However, the mechanisms by which DROSHA affects the lung inflammation during idiopathic pulmonary fi...
Autores principales: | Cho, Soo Jung, Hong, Kyoung Sook, Jeong, Ji Hun, Lee, Mihye, Choi, Augustine M. K., Stout-Delgado, Heather W., Moon, Jong-Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721825/ https://www.ncbi.nlm.nih.gov/pubmed/31434287 http://dx.doi.org/10.3390/cells8080938 |
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