A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer

Irinotecan is a cytotoxic medication used to treat various cancers. Diffuse alveolar hemorrhage (DAH) and interstitial pulmonary disease (IPD) are both serious and life-threatening complications, which are rarely reported to be associated with irinotecan. In our case, however, a pancreatic cancer pa...

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Detalles Bibliográficos
Autores principales: Meng, Lingbin, Deng, Bo, Liu, Baoqiong, Majeed, Umair, Wang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721880/
https://www.ncbi.nlm.nih.gov/pubmed/31501733
http://dx.doi.org/10.7759/cureus.5041
Descripción
Sumario:Irinotecan is a cytotoxic medication used to treat various cancers. Diffuse alveolar hemorrhage (DAH) and interstitial pulmonary disease (IPD) are both serious and life-threatening complications, which are rarely reported to be associated with irinotecan. In our case, however, a pancreatic cancer patient developed both DAH and IPD after administration of irinotecan with fluorouracil (5FU).

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