A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer

Irinotecan is a cytotoxic medication used to treat various cancers. Diffuse alveolar hemorrhage (DAH) and interstitial pulmonary disease (IPD) are both serious and life-threatening complications, which are rarely reported to be associated with irinotecan. In our case, however, a pancreatic cancer pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Lingbin, Deng, Bo, Liu, Baoqiong, Majeed, Umair, Wang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721880/
https://www.ncbi.nlm.nih.gov/pubmed/31501733
http://dx.doi.org/10.7759/cureus.5041
_version_ 1783448436146700288
author Meng, Lingbin
Deng, Bo
Liu, Baoqiong
Majeed, Umair
Wang, Wen
author_facet Meng, Lingbin
Deng, Bo
Liu, Baoqiong
Majeed, Umair
Wang, Wen
author_sort Meng, Lingbin
collection PubMed
description Irinotecan is a cytotoxic medication used to treat various cancers. Diffuse alveolar hemorrhage (DAH) and interstitial pulmonary disease (IPD) are both serious and life-threatening complications, which are rarely reported to be associated with irinotecan. In our case, however, a pancreatic cancer patient developed both DAH and IPD after administration of irinotecan with fluorouracil (5FU).
format Online
Article
Text
id pubmed-6721880
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-67218802019-09-09 A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer Meng, Lingbin Deng, Bo Liu, Baoqiong Majeed, Umair Wang, Wen Cureus Internal Medicine Irinotecan is a cytotoxic medication used to treat various cancers. Diffuse alveolar hemorrhage (DAH) and interstitial pulmonary disease (IPD) are both serious and life-threatening complications, which are rarely reported to be associated with irinotecan. In our case, however, a pancreatic cancer patient developed both DAH and IPD after administration of irinotecan with fluorouracil (5FU). Cureus 2019-06-29 /pmc/articles/PMC6721880/ /pubmed/31501733 http://dx.doi.org/10.7759/cureus.5041 Text en Copyright © 2019, Meng et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Meng, Lingbin
Deng, Bo
Liu, Baoqiong
Majeed, Umair
Wang, Wen
A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer
title A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer
title_full A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer
title_fullStr A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer
title_full_unstemmed A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer
title_short A Rare Case of Irinotecan-induced Interstitial Pulmonary Disease and Diffuse Alveolar Hemorrhage in a Patient with Pancreatic Cancer
title_sort rare case of irinotecan-induced interstitial pulmonary disease and diffuse alveolar hemorrhage in a patient with pancreatic cancer
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721880/
https://www.ncbi.nlm.nih.gov/pubmed/31501733
http://dx.doi.org/10.7759/cureus.5041
work_keys_str_mv AT menglingbin ararecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT dengbo ararecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT liubaoqiong ararecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT majeedumair ararecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT wangwen ararecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT menglingbin rarecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT dengbo rarecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT liubaoqiong rarecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT majeedumair rarecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer
AT wangwen rarecaseofirinotecaninducedinterstitialpulmonarydiseaseanddiffusealveolarhemorrhageinapatientwithpancreaticcancer

Ejemplares similares