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Metastatic Tumour to the Mandible - A Diagnostic and Management Dilemma

Metastatic tumours of the jaw are overlooked due to their relatively rare incidence. However, they are often the first indicators of an unknown primary malignant lesion. In this case report, we present a 68-year-old male patient with a suspected intraosseous malignancy of the mandible who was treate...

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Autores principales: George, Rinku, Neralla, Mahathi, Rajan, Jyotsna, Haque, Ahmed Elham, Kumar, Santhosh P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721909/
https://www.ncbi.nlm.nih.gov/pubmed/31516800
http://dx.doi.org/10.7759/cureus.5093
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author George, Rinku
Neralla, Mahathi
Rajan, Jyotsna
Haque, Ahmed Elham
Kumar, Santhosh P
author_facet George, Rinku
Neralla, Mahathi
Rajan, Jyotsna
Haque, Ahmed Elham
Kumar, Santhosh P
author_sort George, Rinku
collection PubMed
description Metastatic tumours of the jaw are overlooked due to their relatively rare incidence. However, they are often the first indicators of an unknown primary malignant lesion. In this case report, we present a 68-year-old male patient with a suspected intraosseous malignancy of the mandible who was treated by a right segmental mandibulectomy. The final histopathology report was indicative of a secondary metastatic tumour. Positron emission tomography scan revealed a suspicious lesion in the right lung, which was identified as the primary tumour by biopsy using the Tru-Cut® biopsy device (MeritMedical, Jordan UT). The metastatic lesion to the oral soft tissues was easily recognized, in contrast to the jawbone metastasis. Differentiating between primary intraosseous and metastatic mandibular tumours relies on the histopathologist and the surgeon working in tandem to arrive at an early conclusive diagnosis. Knowledge of metastatic tumours to the facial bones is indispensable to a surgeon as it can often be the first indication of an unknown primary malignancy. Identification of early signs, appropriate and timely investigative procedures, coordination between pathologist and surgeon, and choosing the correct treatment modality can help prolong and improve the quality of life of the patient.
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spelling pubmed-67219092019-09-12 Metastatic Tumour to the Mandible - A Diagnostic and Management Dilemma George, Rinku Neralla, Mahathi Rajan, Jyotsna Haque, Ahmed Elham Kumar, Santhosh P Cureus Pain Management Metastatic tumours of the jaw are overlooked due to their relatively rare incidence. However, they are often the first indicators of an unknown primary malignant lesion. In this case report, we present a 68-year-old male patient with a suspected intraosseous malignancy of the mandible who was treated by a right segmental mandibulectomy. The final histopathology report was indicative of a secondary metastatic tumour. Positron emission tomography scan revealed a suspicious lesion in the right lung, which was identified as the primary tumour by biopsy using the Tru-Cut® biopsy device (MeritMedical, Jordan UT). The metastatic lesion to the oral soft tissues was easily recognized, in contrast to the jawbone metastasis. Differentiating between primary intraosseous and metastatic mandibular tumours relies on the histopathologist and the surgeon working in tandem to arrive at an early conclusive diagnosis. Knowledge of metastatic tumours to the facial bones is indispensable to a surgeon as it can often be the first indication of an unknown primary malignancy. Identification of early signs, appropriate and timely investigative procedures, coordination between pathologist and surgeon, and choosing the correct treatment modality can help prolong and improve the quality of life of the patient. Cureus 2019-07-07 /pmc/articles/PMC6721909/ /pubmed/31516800 http://dx.doi.org/10.7759/cureus.5093 Text en Copyright © 2019, George et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pain Management
George, Rinku
Neralla, Mahathi
Rajan, Jyotsna
Haque, Ahmed Elham
Kumar, Santhosh P
Metastatic Tumour to the Mandible - A Diagnostic and Management Dilemma
title Metastatic Tumour to the Mandible - A Diagnostic and Management Dilemma
title_full Metastatic Tumour to the Mandible - A Diagnostic and Management Dilemma
title_fullStr Metastatic Tumour to the Mandible - A Diagnostic and Management Dilemma
title_full_unstemmed Metastatic Tumour to the Mandible - A Diagnostic and Management Dilemma
title_short Metastatic Tumour to the Mandible - A Diagnostic and Management Dilemma
title_sort metastatic tumour to the mandible - a diagnostic and management dilemma
topic Pain Management
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721909/
https://www.ncbi.nlm.nih.gov/pubmed/31516800
http://dx.doi.org/10.7759/cureus.5093
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