BK Virus-associated Nephropathy in a Patient with T Cell Leukemia/Lymphoma Syndrome

BK virus-associated nephropathy develops in renal transplant patients with the main manifestation of tubulointerstitial nephritis or ureteral stenosis. Nephrotic syndrome is a rare manifestation of BK virus-associated nephropathy. Here we report a case of a 69-year-old female presenting with nephrot...

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Autores principales: Liu, Baoqiong, Meng, Lingbin, Guan, Xuan, Yang, Yifeng, Manoucheri, Manoucher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721923/
https://www.ncbi.nlm.nih.gov/pubmed/31516781
http://dx.doi.org/10.7759/cureus.5070
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author Liu, Baoqiong
Meng, Lingbin
Guan, Xuan
Yang, Yifeng
Manoucheri, Manoucher
author_facet Liu, Baoqiong
Meng, Lingbin
Guan, Xuan
Yang, Yifeng
Manoucheri, Manoucher
author_sort Liu, Baoqiong
collection PubMed
description BK virus-associated nephropathy develops in renal transplant patients with the main manifestation of tubulointerstitial nephritis or ureteral stenosis. Nephrotic syndrome is a rare manifestation of BK virus-associated nephropathy. Here we report a case of a 69-year-old female presenting with nephrotic and nephritic syndrome related to BK virus infection. Kidney biopsy revealed severe acute tubular injury, collapsing glomerulopathy, and focal microangiopathic changes. Four weeks of leflunomide and intravenous immunoglobulin (IVIG) resulted in the recovery of kidney function and improvement of proteinuria. 
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spelling pubmed-67219232019-09-12 BK Virus-associated Nephropathy in a Patient with T Cell Leukemia/Lymphoma Syndrome Liu, Baoqiong Meng, Lingbin Guan, Xuan Yang, Yifeng Manoucheri, Manoucher Cureus Internal Medicine BK virus-associated nephropathy develops in renal transplant patients with the main manifestation of tubulointerstitial nephritis or ureteral stenosis. Nephrotic syndrome is a rare manifestation of BK virus-associated nephropathy. Here we report a case of a 69-year-old female presenting with nephrotic and nephritic syndrome related to BK virus infection. Kidney biopsy revealed severe acute tubular injury, collapsing glomerulopathy, and focal microangiopathic changes. Four weeks of leflunomide and intravenous immunoglobulin (IVIG) resulted in the recovery of kidney function and improvement of proteinuria.  Cureus 2019-07-02 /pmc/articles/PMC6721923/ /pubmed/31516781 http://dx.doi.org/10.7759/cureus.5070 Text en Copyright © 2019, Liu et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Liu, Baoqiong
Meng, Lingbin
Guan, Xuan
Yang, Yifeng
Manoucheri, Manoucher
BK Virus-associated Nephropathy in a Patient with T Cell Leukemia/Lymphoma Syndrome
title BK Virus-associated Nephropathy in a Patient with T Cell Leukemia/Lymphoma Syndrome
title_full BK Virus-associated Nephropathy in a Patient with T Cell Leukemia/Lymphoma Syndrome
title_fullStr BK Virus-associated Nephropathy in a Patient with T Cell Leukemia/Lymphoma Syndrome
title_full_unstemmed BK Virus-associated Nephropathy in a Patient with T Cell Leukemia/Lymphoma Syndrome
title_short BK Virus-associated Nephropathy in a Patient with T Cell Leukemia/Lymphoma Syndrome
title_sort bk virus-associated nephropathy in a patient with t cell leukemia/lymphoma syndrome
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721923/
https://www.ncbi.nlm.nih.gov/pubmed/31516781
http://dx.doi.org/10.7759/cureus.5070
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