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Extreme inbreeding in a European ancestry sample from the contemporary UK population
In most human societies, there are taboos and laws banning mating between first- and second-degree relatives, but actual prevalence and effects on health and fitness are poorly quantified. Here, we leverage a large observational study of ~450,000 participants of European ancestry from the UK Biobank...
Autores principales: | Yengo, Loic, Wray, Naomi R., Visscher, Peter M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722066/ https://www.ncbi.nlm.nih.gov/pubmed/31481654 http://dx.doi.org/10.1038/s41467-019-11724-6 |
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