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Extreme inbreeding in a European ancestry sample from the contemporary UK population

In most human societies, there are taboos and laws banning mating between first- and second-degree relatives, but actual prevalence and effects on health and fitness are poorly quantified. Here, we leverage a large observational study of ~450,000 participants of European ancestry from the UK Biobank...

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Detalles Bibliográficos
Autores principales: Yengo, Loic, Wray, Naomi R., Visscher, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722066/
https://www.ncbi.nlm.nih.gov/pubmed/31481654
http://dx.doi.org/10.1038/s41467-019-11724-6

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