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A “human knockout” model to investigate the influence of the α-actinin-3 protein on exercise-induced mitochondrial adaptations
Research in α-actinin-3 knockout mice suggests a novel role for α-actinin-3 as a mediator of cell signalling. We took advantage of naturally-occurring human “knockouts” (lacking α-actinin-3 protein) to investigate the consequences of α-actinin-3 deficiency on exercise-induced changes in mitochondria...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722100/ https://www.ncbi.nlm.nih.gov/pubmed/31481717 http://dx.doi.org/10.1038/s41598-019-49042-y |