Cargando…
TRIM21—From Intracellular Immunity to Therapy
Tripartite motif containing-21 (TRIM21) is a cytosolic ubiquitin ligase and antibody receptor that provides a last line of defense against invading viruses. It does so by acting as a sensor that intercepts antibody-coated viruses that have evaded extracellular neutralization and breached the cell me...
Autores principales: | Foss, Stian, Bottermann, Maria, Jonsson, Alexandra, Sandlie, Inger, James, Leo C., Andersen, Jan Terje |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722209/ https://www.ncbi.nlm.nih.gov/pubmed/31555278 http://dx.doi.org/10.3389/fimmu.2019.02049 |
Ejemplares similares
-
Antibody-antigen kinetics constrain intracellular humoral immunity
por: Bottermann, Maria, et al.
Publicado: (2016) -
TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity
por: Foss, Stian, et al.
Publicado: (2015) -
Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity
por: Bottermann, Maria, et al.
Publicado: (2017) -
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
por: Caddy, Sarah L, et al.
Publicado: (2020) -
TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
por: Bottermann, Maria, et al.
Publicado: (2018)