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Nucleoporin insufficiency disrupts a pluripotent regulatory circuit in a pro-arrhythmogenic stem cell line

Nucleoporins have been reported to regulate pluripotent biology, but how they do so remains partially characterized. This study examined the effects of nup155 gene disruption on mouse embryonic stem cells to gain insights into possible mechanisms by which nucleoporins regulate pluripotency in a pro-...

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Detalles Bibliográficos
Autores principales: Preston, Claudia C., Storm, Emily C., Burdine, Ryan D., Bradley, Tyler A., Uttecht, Andrew D., Faustino, Randolph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722237/
https://www.ncbi.nlm.nih.gov/pubmed/31481660
http://dx.doi.org/10.1038/s41598-019-49147-4