Cargando…
Nucleoporin insufficiency disrupts a pluripotent regulatory circuit in a pro-arrhythmogenic stem cell line
Nucleoporins have been reported to regulate pluripotent biology, but how they do so remains partially characterized. This study examined the effects of nup155 gene disruption on mouse embryonic stem cells to gain insights into possible mechanisms by which nucleoporins regulate pluripotency in a pro-...
Autores principales: | Preston, Claudia C., Storm, Emily C., Burdine, Ryan D., Bradley, Tyler A., Uttecht, Andrew D., Faustino, Randolph S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722237/ https://www.ncbi.nlm.nih.gov/pubmed/31481660 http://dx.doi.org/10.1038/s41598-019-49147-4 |
Ejemplares similares
-
NUP155 insufficiency recalibrates a pluripotent transcriptome with network remodeling of a cardiogenic signaling module
por: Preston, Claudia C., et al.
Publicado: (2018) -
Maternal High Fat Diet and Diabetes Disrupts Transcriptomic Pathways That Regulate Cardiac Metabolism and Cell Fate in Newborn Rat Hearts
por: Preston, Claudia C., et al.
Publicado: (2020) -
The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing
por: Jacinto, Filipe V., et al.
Publicado: (2015) -
Altered localization of nucleoporin 98 in primary tauopathies
por: Dickson, John R, et al.
Publicado: (2022) -
Nuclear Envelope Regulation of Oncogenic Processes: Roles in Pancreatic Cancer
por: Preston, Claudia C., et al.
Publicado: (2018)