Cargando…

Assessing the Protective Metabolome Using Machine Learning in World Trade Center Particulate Exposed Firefighters at Risk for Lung Injury

The metabolome of World Trade Center (WTC) particulate matter (PM) exposure has yet to be fully defined and may yield information that will further define bioactive pathways relevant to lung injury. A subset of Fire Department of New York firefighters demonstrated resistance to subsequent loss of lu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crowley, George, Kwon, Sophia, Ostrofsky, Dean F., Clementi, Emily A., Haider, Syed Hissam, Caraher, Erin J., Lam, Rachel, St-Jules, David E., Liu, Mengling, Prezant, David J., Nolan, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722247/ https://www.ncbi.nlm.nih.gov/pubmed/31481674 http://dx.doi.org/10.1038/s41598-019-48458-w

Ejemplares similares

Metabolomics of World Trade Center-Lung Injury: a machine learning approach
por: Crowley, George, et al.
Publicado: (2018)

Predictive Biomarkers of Gastroesophageal Reflux Disease and Barrett’s Esophagus in World Trade Center Exposed Firefighters: a 15 Year Longitudinal Study
por: Haider, Syed H., et al.
Publicado: (2018)

Synergistic Effect of WTC-Particulate Matter and Lysophosphatidic Acid Exposure and the Role of RAGE: In-Vitro and Translational Assessment
por: Lam, Rachel, et al.
Publicado: (2020)

World Trade Center-Cardiorespiratory and Vascular Dysfunction: Assessing the Phenotype and Metabolome of a Murine Particulate Matter Exposure Model
por: Veerappan, Arul, et al.
Publicado: (2020)

YKL-40 is a Protective Biomarker for Fatty Liver in World Trade Center Particulate Matter-Exposed Firefighters
por: Cho, Soo Jung, et al.
Publicado: (2014)

Author Correction: World Trade Center-Cardiorespiratory and Vascular Dysfunction: Assessing the Phenotype and Metabolome of a Murine Particulate Matter Exposure Model
por: Veerappan, Arul, et al.
Publicado: (2021)

2346: Receptor for advanced glycation end-products: Mitigating the persistent effects of particulate matter induced airway injury
por: Hissam Haider, Syed, et al.
Publicado: (2018)

Receptor for advanced glycation end-products and World Trade Center particulate induced lung function loss: A case-cohort study and murine model of acute particulate exposure
por: Caraher, Erin J., et al.
Publicado: (2017)

2372: Metabolite and biomarker predictors of WTC-lung injury: An integrated multiplatform pilot analysis
por: Crowley, George, et al.
Publicado: (2018)

Quantitative lung morphology: semi-automated measurement of mean linear intercept
por: Crowley, George, et al.
Publicado: (2019)

Metabolic Syndrome Biomarkers of World Trade Center Airway Hyperreactivity: A 16-Year Prospective Cohort Study
por: Kwon, Sophia, et al.
Publicado: (2019)

Trends in Respiratory Symptoms of Firefighters Exposed to the World Trade Center Disaster: 2001–2005
por: Webber, Mayris P., et al.
Publicado: (2009)

4088 Longitudinal Assessment of Metabolic Syndrome as a Modifiable Risk factor of World Trade Center Particulate Matter Exposure Associated Lung Disease
por: Kwon, Sophia, et al.
Publicado: (2020)

Multiple Myeloma and Its Precursor Disease Among Firefighters Exposed to the World Trade Center Disaster
por: Landgren, Ola, et al.
Publicado: (2018)

Induced Sputum Assessment in New York City Firefighters Exposed to World Trade Center Dust
por: Fireman, Elizabeth M., et al.
Publicado: (2004)

Cancer incidence in World Trade Center-exposed and non-exposed male firefighters, as compared with the US adult male population: 2001–2016
por: Webber, Mayris P, et al.
Publicado: (2021)

Post-9/11 Peripheral Neuropathy Symptoms among World Trade Center-Exposed Firefighters and Emergency Medical Service Workers
por: Colbeth, Hilary L., et al.
Publicado: (2019)

Fluid resuscitation-associated increased mortality and inflammatory cytokine expression in murine polymicrobial sepsis
por: Lee, Young Im, et al.
Publicado: (2017)

Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Protocol: A Randomized Clinical Trial
por: Kwon, Sophia, et al.
Publicado: (2020)

PEDF, a pleiotropic WTC-LI biomarker: Machine learning biomarker identification and validation
por: Crowley, George, et al.
Publicado: (2021)

Early Elevation of Serum MMP-3 and MMP-12 Predicts Protection from World Trade Center-Lung Injury in New York City Firefighters: A Nested Case-Control Study
por: Kwon, Sophia, et al.
Publicado: (2013)

282 Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE): a Proof of Concept Randomized Clinical Trial
por: Kwon, Sophia, et al.
Publicado: (2023)

The effect of World Trade Center exposure on the latency of chronic rhinosinusitis diagnoses in New York City firefighters: 2001–2011
por: Weakley, Jessica, et al.
Publicado: (2016)

Metabolic Syndrome and Air Pollution: A Narrative Review of Their Cardiopulmonary Effects
por: Clementi, Emily A., et al.
Publicado: (2019)

Long-term Cardiovascular Disease Risk Among Firefighters After the World Trade Center Disaster
por: Cohen, Hillel W., et al.
Publicado: (2019)

MMP-2 and TIMP-1 predict healing of WTC-lung injury in New York City firefighters
por: Nolan, Anna, et al.
Publicado: (2014)

Serum Th‐2 cytokines and FEV(1) decline in WTC‐exposed firefighters: A 19‐year longitudinal study
por: Weiden, Michael D., et al.
Publicado: (2021)

Biomonitoring of chemical exposure among New York City firefighters responding to the World Trade Center fire and collapse.
por: Edelman, Philip, et al.
Publicado: (2003)

Dietary phenotype and advanced glycation end-products predict WTC-obstructive airways disease: a longitudinal observational study
por: Lam, Rachel, et al.
Publicado: (2021)

Subclinical Hearing Deficits in Noise-Exposed Firefighters
por: Snapp, Hillary A., et al.
Publicado: (2022)

Peripheral vestibular loss in noise-exposed firefighters
por: Snapp, Hillary Anne, et al.
Publicado: (2023)

Genomics of Particulate Matter Exposure Associated Cardiopulmonary Disease: A Narrative Review
por: Citron, Julia, et al.
Publicado: (2019)

Mortality among Fire Department of the City of New York Rescue and Recovery Workers Exposed to the World Trade Center Disaster, 2001–2017
por: Colbeth, Hilary L., et al.
Publicado: (2020)

Receptor for advanced glycation end-products and environmental exposure related obstructive airways disease: a systematic review
por: Haider, Syed H., et al.
Publicado: (2019)

Severe Acute Respiratory Syndrome and Particulate Matter Exposure: A Systematic Review
por: Podury, Sanjiti, et al.
Publicado: (2023)

Medical Leave Associated With COVID-19 Among Emergency Medical System Responders and Firefighters in New York City
por: Prezant, David J., et al.
Publicado: (2020)

Myeloma precursor disease (MGUS) among rescue and recovery workers exposed to the World Trade Center disaster
por: Zeig-Owens, Rachel, et al.
Publicado: (2022)

Twenty-Year Reflection on the Impact of World Trade Center Exposure on Pulmonary Outcomes in Fire Department of the City of New York (FDNY) Rescue and Recovery Workers
por: Cleven, Krystal L., et al.
Publicado: (2021)

Profiling and predicting help-seeking behaviour among trauma-exposed UK firefighters
por: Tamrakar, T., et al.
Publicado: (2020)

Structural and Resting-State Brain Alterations in Trauma-Exposed Firefighters: Preliminary Results
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kcq5c2v0addvhu4up0i017e4t5