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Successful Treatment of Hereditary Hemorrhagic Telangiectasia With Octreotide

Hereditary hemorrhagic telangiectasia (HHT) is a disorder characterized by telangiectasias and arteriovenous malformations. We present a case report of a 74-year-old man diagnosed with HHT having a favorable response to a somatostatin analogue for treatment. This patient had been suffering from chro...

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Autores principales: Houghton, Kimberly D., Umar, Beena, Schairer, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722341/
https://www.ncbi.nlm.nih.gov/pubmed/31616764
http://dx.doi.org/10.14309/crj.0000000000000088
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author Houghton, Kimberly D.
Umar, Beena
Schairer, Jason
author_facet Houghton, Kimberly D.
Umar, Beena
Schairer, Jason
author_sort Houghton, Kimberly D.
collection PubMed
description Hereditary hemorrhagic telangiectasia (HHT) is a disorder characterized by telangiectasias and arteriovenous malformations. We present a case report of a 74-year-old man diagnosed with HHT having a favorable response to a somatostatin analogue for treatment. This patient had been suffering from chronic anemia from recurrent gastrointestinal bleeding, requiring oral/intravenous iron replacement, frequent endoscopic ablations, and blood transfusions. Due to insufficient treatment, he was started on subcutaneous octreotide, with significant improvement as evidenced by a steady increase in the hemoglobin level, decreased endoscopic interventions, and decreased blood transfusions, making this the first case of HHT successfully treated with octreotide.
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spelling pubmed-67223412019-10-15 Successful Treatment of Hereditary Hemorrhagic Telangiectasia With Octreotide Houghton, Kimberly D. Umar, Beena Schairer, Jason ACG Case Rep J Case Report Hereditary hemorrhagic telangiectasia (HHT) is a disorder characterized by telangiectasias and arteriovenous malformations. We present a case report of a 74-year-old man diagnosed with HHT having a favorable response to a somatostatin analogue for treatment. This patient had been suffering from chronic anemia from recurrent gastrointestinal bleeding, requiring oral/intravenous iron replacement, frequent endoscopic ablations, and blood transfusions. Due to insufficient treatment, he was started on subcutaneous octreotide, with significant improvement as evidenced by a steady increase in the hemoglobin level, decreased endoscopic interventions, and decreased blood transfusions, making this the first case of HHT successfully treated with octreotide. Wolters Kluwer 2019-06-10 /pmc/articles/PMC6722341/ /pubmed/31616764 http://dx.doi.org/10.14309/crj.0000000000000088 Text en © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND (http://CreativeCommonsAttribution-NonCommercial-NoDerivativesLicense4.0(CCBY-NC-ND) ), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Houghton, Kimberly D.
Umar, Beena
Schairer, Jason
Successful Treatment of Hereditary Hemorrhagic Telangiectasia With Octreotide
title Successful Treatment of Hereditary Hemorrhagic Telangiectasia With Octreotide
title_full Successful Treatment of Hereditary Hemorrhagic Telangiectasia With Octreotide
title_fullStr Successful Treatment of Hereditary Hemorrhagic Telangiectasia With Octreotide
title_full_unstemmed Successful Treatment of Hereditary Hemorrhagic Telangiectasia With Octreotide
title_short Successful Treatment of Hereditary Hemorrhagic Telangiectasia With Octreotide
title_sort successful treatment of hereditary hemorrhagic telangiectasia with octreotide
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722341/
https://www.ncbi.nlm.nih.gov/pubmed/31616764
http://dx.doi.org/10.14309/crj.0000000000000088
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