Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease

Ganglioneuromas (GNs) are hamartomatous tumors derived from the autonomic nervous system. GNs are frequently associated with neurofibromatosis-1 and multiple endocrine neoplasia type 2b and commonly present with constipation, abdominal pain, weight loss, obstruction, and gastrointestinal bleeding. W...

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Autores principales: Badrinath, Madhuri, Mandru, Rachana, Lowe, Dhruv, Manocha, Divey, Achufusi, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722376/
https://www.ncbi.nlm.nih.gov/pubmed/31620517
http://dx.doi.org/10.14309/crj.0000000000000114
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author Badrinath, Madhuri
Mandru, Rachana
Lowe, Dhruv
Manocha, Divey
Achufusi, Ted
author_facet Badrinath, Madhuri
Mandru, Rachana
Lowe, Dhruv
Manocha, Divey
Achufusi, Ted
author_sort Badrinath, Madhuri
collection PubMed
description Ganglioneuromas (GNs) are hamartomatous tumors derived from the autonomic nervous system. GNs are frequently associated with neurofibromatosis-1 and multiple endocrine neoplasia type 2b and commonly present with constipation, abdominal pain, weight loss, obstruction, and gastrointestinal bleeding. We report a 40-year-old man with symptoms of chronic abdominal pain, weight loss, and diarrhea for 1 year. Imaging was suggestive of thickening of ileal wall with a stricture, and subsequent biopsy revealed intestinal GN. To our knowledge, this is the first case report of an isolated intestinal GN masquerading as Crohn's disease.
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spelling pubmed-67223762019-10-16 Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease Badrinath, Madhuri Mandru, Rachana Lowe, Dhruv Manocha, Divey Achufusi, Ted ACG Case Rep J Case Report Ganglioneuromas (GNs) are hamartomatous tumors derived from the autonomic nervous system. GNs are frequently associated with neurofibromatosis-1 and multiple endocrine neoplasia type 2b and commonly present with constipation, abdominal pain, weight loss, obstruction, and gastrointestinal bleeding. We report a 40-year-old man with symptoms of chronic abdominal pain, weight loss, and diarrhea for 1 year. Imaging was suggestive of thickening of ileal wall with a stricture, and subsequent biopsy revealed intestinal GN. To our knowledge, this is the first case report of an isolated intestinal GN masquerading as Crohn's disease. Wolters Kluwer 2019-07-11 /pmc/articles/PMC6722376/ /pubmed/31620517 http://dx.doi.org/10.14309/crj.0000000000000114 Text en © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Badrinath, Madhuri
Mandru, Rachana
Lowe, Dhruv
Manocha, Divey
Achufusi, Ted
Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease
title Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease
title_full Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease
title_fullStr Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease
title_full_unstemmed Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease
title_short Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease
title_sort isolated intestinal ganglioneuroma mimicking small bowel crohn's disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722376/
https://www.ncbi.nlm.nih.gov/pubmed/31620517
http://dx.doi.org/10.14309/crj.0000000000000114
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