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Cryo-EM structure of the Ustilago maydis kinesin-5 motor domain bound to microtubules
In many eukaryotes, kinesin-5 motors are essential for mitosis, and small molecules that inhibit human kinesin-5 disrupt cell division. To investigate whether fungal kinesin-5s could be targets for novel fungicides, we studied kinesin-5 from the pathogenic fungus Ustilago maydis. We used cryo-electr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Academic Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722389/ https://www.ncbi.nlm.nih.gov/pubmed/31288039 http://dx.doi.org/10.1016/j.jsb.2019.07.003 |