Quercetin-3-Rutinoside Blocks the Disassembly of Cholera Toxin by Protein Disulfide Isomerase

Protein disulfide isomerase (PDI) is mainly located in the endoplasmic reticulum (ER) but is also secreted into the bloodstream where its oxidoreductase activity is involved with thrombus formation. Quercetin-3-rutinoside (Q3R) blocks this activity, but its inhibitory mechanism against PDI is not fu...

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Detalles Bibliográficos
Autores principales: Guyette, Jessica, Cherubin, Patrick, Serrano, Albert, Taylor, Michael, Abedin, Faisal, O’Donnell, Morgan, Burress, Helen, Tatulian, Suren A., Teter, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722528/
https://www.ncbi.nlm.nih.gov/pubmed/31382673
http://dx.doi.org/10.3390/toxins11080458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722528/
https://www.ncbi.nlm.nih.gov/pubmed/31382673
http://dx.doi.org/10.3390/toxins11080458

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