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Quercetin-3-Rutinoside Blocks the Disassembly of Cholera Toxin by Protein Disulfide Isomerase
Protein disulfide isomerase (PDI) is mainly located in the endoplasmic reticulum (ER) but is also secreted into the bloodstream where its oxidoreductase activity is involved with thrombus formation. Quercetin-3-rutinoside (Q3R) blocks this activity, but its inhibitory mechanism against PDI is not fu...
Autores principales: | Guyette, Jessica, Cherubin, Patrick, Serrano, Albert, Taylor, Michael, Abedin, Faisal, O’Donnell, Morgan, Burress, Helen, Tatulian, Suren A., Teter, Ken |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722528/ https://www.ncbi.nlm.nih.gov/pubmed/31382673 http://dx.doi.org/10.3390/toxins11080458 |
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