Cargando…

Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit

The diagnosis and management of seizures in the critically ill patient can sometimes present a unique challenge for practitioners due to lack of exposure and complex patient comorbidities. The reported incidence varies between 8% and 34% of critically ill patients, with many patients often showing n...

Descripción completa

Detalles Bibliográficos
Autores principales: Strein, Micheal, Holton-Burke, John P., Smith, LaTangela R., Brophy, Gretchen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722541/
https://www.ncbi.nlm.nih.gov/pubmed/31394791
http://dx.doi.org/10.3390/jcm8081177
_version_ 1783448561358209024
author Strein, Micheal
Holton-Burke, John P.
Smith, LaTangela R.
Brophy, Gretchen M.
author_facet Strein, Micheal
Holton-Burke, John P.
Smith, LaTangela R.
Brophy, Gretchen M.
author_sort Strein, Micheal
collection PubMed
description The diagnosis and management of seizures in the critically ill patient can sometimes present a unique challenge for practitioners due to lack of exposure and complex patient comorbidities. The reported incidence varies between 8% and 34% of critically ill patients, with many patients often showing no overt clinical signs of seizures. Outcomes in patients with unidentified seizure activity tend to be poor, and mortality significantly increases in those who have seizure activity longer than 30 min. Prompt diagnosis and provision of medical therapy are crucial in order to attain successful seizure termination and prevent poor outcomes. In this article, we review the epidemiology and pathophysiology of seizures in the critically ill, various seizure monitoring modalities, and recommended medical therapy.
format Online
Article
Text
id pubmed-6722541
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-67225412019-09-10 Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit Strein, Micheal Holton-Burke, John P. Smith, LaTangela R. Brophy, Gretchen M. J Clin Med Review The diagnosis and management of seizures in the critically ill patient can sometimes present a unique challenge for practitioners due to lack of exposure and complex patient comorbidities. The reported incidence varies between 8% and 34% of critically ill patients, with many patients often showing no overt clinical signs of seizures. Outcomes in patients with unidentified seizure activity tend to be poor, and mortality significantly increases in those who have seizure activity longer than 30 min. Prompt diagnosis and provision of medical therapy are crucial in order to attain successful seizure termination and prevent poor outcomes. In this article, we review the epidemiology and pathophysiology of seizures in the critically ill, various seizure monitoring modalities, and recommended medical therapy. MDPI 2019-08-07 /pmc/articles/PMC6722541/ /pubmed/31394791 http://dx.doi.org/10.3390/jcm8081177 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Strein, Micheal
Holton-Burke, John P.
Smith, LaTangela R.
Brophy, Gretchen M.
Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit
title Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit
title_full Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit
title_fullStr Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit
title_full_unstemmed Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit
title_short Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit
title_sort prevention, treatment, and monitoring of seizures in the intensive care unit
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722541/
https://www.ncbi.nlm.nih.gov/pubmed/31394791
http://dx.doi.org/10.3390/jcm8081177
work_keys_str_mv AT streinmicheal preventiontreatmentandmonitoringofseizuresintheintensivecareunit
AT holtonburkejohnp preventiontreatmentandmonitoringofseizuresintheintensivecareunit
AT smithlatangelar preventiontreatmentandmonitoringofseizuresintheintensivecareunit
AT brophygretchenm preventiontreatmentandmonitoringofseizuresintheintensivecareunit