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Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit
The diagnosis and management of seizures in the critically ill patient can sometimes present a unique challenge for practitioners due to lack of exposure and complex patient comorbidities. The reported incidence varies between 8% and 34% of critically ill patients, with many patients often showing n...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722541/ https://www.ncbi.nlm.nih.gov/pubmed/31394791 http://dx.doi.org/10.3390/jcm8081177 |
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author | Strein, Micheal Holton-Burke, John P. Smith, LaTangela R. Brophy, Gretchen M. |
author_facet | Strein, Micheal Holton-Burke, John P. Smith, LaTangela R. Brophy, Gretchen M. |
author_sort | Strein, Micheal |
collection | PubMed |
description | The diagnosis and management of seizures in the critically ill patient can sometimes present a unique challenge for practitioners due to lack of exposure and complex patient comorbidities. The reported incidence varies between 8% and 34% of critically ill patients, with many patients often showing no overt clinical signs of seizures. Outcomes in patients with unidentified seizure activity tend to be poor, and mortality significantly increases in those who have seizure activity longer than 30 min. Prompt diagnosis and provision of medical therapy are crucial in order to attain successful seizure termination and prevent poor outcomes. In this article, we review the epidemiology and pathophysiology of seizures in the critically ill, various seizure monitoring modalities, and recommended medical therapy. |
format | Online Article Text |
id | pubmed-6722541 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-67225412019-09-10 Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit Strein, Micheal Holton-Burke, John P. Smith, LaTangela R. Brophy, Gretchen M. J Clin Med Review The diagnosis and management of seizures in the critically ill patient can sometimes present a unique challenge for practitioners due to lack of exposure and complex patient comorbidities. The reported incidence varies between 8% and 34% of critically ill patients, with many patients often showing no overt clinical signs of seizures. Outcomes in patients with unidentified seizure activity tend to be poor, and mortality significantly increases in those who have seizure activity longer than 30 min. Prompt diagnosis and provision of medical therapy are crucial in order to attain successful seizure termination and prevent poor outcomes. In this article, we review the epidemiology and pathophysiology of seizures in the critically ill, various seizure monitoring modalities, and recommended medical therapy. MDPI 2019-08-07 /pmc/articles/PMC6722541/ /pubmed/31394791 http://dx.doi.org/10.3390/jcm8081177 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Strein, Micheal Holton-Burke, John P. Smith, LaTangela R. Brophy, Gretchen M. Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit |
title | Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit |
title_full | Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit |
title_fullStr | Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit |
title_full_unstemmed | Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit |
title_short | Prevention, Treatment, and Monitoring of Seizures in the Intensive Care Unit |
title_sort | prevention, treatment, and monitoring of seizures in the intensive care unit |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722541/ https://www.ncbi.nlm.nih.gov/pubmed/31394791 http://dx.doi.org/10.3390/jcm8081177 |
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