Thimet Oligopeptidase (EC 3.4.24.15) Key Functions Suggested by Knockout Mice Phenotype Characterization

Thimet oligopeptidase (THOP1) is thought to be involved in neuropeptide metabolism, antigen presentation, neurodegeneration, and cancer. Herein, the generation of THOP1 C57BL/6 knockout mice (THOP1(−/−)) is described showing that they are viable, have estrus cycle, fertility, and a number of puppies...

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Detalles Bibliográficos
Autores principales: dos Santos, Nilton B., Franco, Roseane D., Camarini, Rosana, Munhoz, Carolina D., Eichler, Rosangela A. S., Gewehr, Mayara C. F., Reckziegel, Patricia, Llanos, Ricardo P., Dale, Camila S., da Silva, Victoria R. O., Borges, Vanessa F., Lima, Braulio H. F., Cunha, Fernando Q., Visniauskas, Bruna, Chagas, Jair R., Tufik, Sergio, Peres, Fernanda F., Abilio, Vanessa C., Florio, Jorge C., Iwai, Leo K., Rioli, Vanessa, Presoto, Benedito C., Guimaraes, Alessander O., Pesquero, Joao B., Bader, Michael, Castro, Leandro M., Ferro, Emer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722639/
https://www.ncbi.nlm.nih.gov/pubmed/31431000
http://dx.doi.org/10.3390/biom9080382

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