Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties

Retinal pigment epithelium (RPE) acts as an outer blood–retinal barrier that limits the access of circulating xenobiotics to the eye. In addition, the RPE limits posterior elimination of intravitreally injected drugs to circulation. Thus, permeation in the RPE has a significant effect on ocular phar...

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Detalles Bibliográficos
Autores principales: Hellinen, Laura, Pirskanen, Lea, Tengvall-Unadike, Unni, Urtti, Arto, Reinisalo, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722654/
https://www.ncbi.nlm.nih.gov/pubmed/31412689
http://dx.doi.org/10.3390/pharmaceutics11080412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722654/
https://www.ncbi.nlm.nih.gov/pubmed/31412689
http://dx.doi.org/10.3390/pharmaceutics11080412

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