Cargando…
Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties
Retinal pigment epithelium (RPE) acts as an outer blood–retinal barrier that limits the access of circulating xenobiotics to the eye. In addition, the RPE limits posterior elimination of intravitreally injected drugs to circulation. Thus, permeation in the RPE has a significant effect on ocular phar...
Autores principales: | Hellinen, Laura, Pirskanen, Lea, Tengvall-Unadike, Unni, Urtti, Arto, Reinisalo, Mika |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722654/ https://www.ncbi.nlm.nih.gov/pubmed/31412689 http://dx.doi.org/10.3390/pharmaceutics11080412 |
Ejemplares similares
-
Retraction: Hellinen et al. Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties. Pharmaceutics 2019, 11, 412
por: Hellinen, Laura, et al.
Publicado: (2022) -
Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model
por: Hellinen, Laura, et al.
Publicado: (2019) -
Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium
por: Pelkonen, Laura, et al.
Publicado: (2016) -
Microflow-Based Device for In Vitro and Ex Vivo Drug Permeability Studies
por: Hemmilä, Samu, et al.
Publicado: (2020) -
Regulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding site
por: Reinisalo, Mika, et al.
Publicado: (2012)