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Dopamine receptor D(2) activation suppresses the radiosensitizing effect of aripiprazole via activation of AMPK

Drug repositioning has garnered attention as an alternative strategy to the discovery and development of novel anticancer drug candidates. In this study, we screened 321 FDA‐approved drugs against nonirradiated and irradiated MCF‐7 cells, revealing that aripiprazole, a dopamine receptor D2 (D2R) par...

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Detalles Bibliográficos
Autores principales:	Lee, Hyounji, Kang, Seongman, Sonn, Jong Kyung, Lim, Young‐Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722896/ https://www.ncbi.nlm.nih.gov/pubmed/31301124 http://dx.doi.org/10.1002/2211-5463.12699

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