Cargando…
Balancing the Photoreceptor Proteome: Proteostasis Network Therapeutics for Inherited Retinal Disease
The light sensing outer segments of photoreceptors (PRs) are renewed every ten days due to their high photoactivity, especially of the cones during daytime vision. This demands a tremendous amount of energy, as well as a high turnover of their main biosynthetic compounds, membranes, and proteins. Th...
Autores principales: | Faber, Siebren, Roepman, Ronald |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722924/ https://www.ncbi.nlm.nih.gov/pubmed/31344897 http://dx.doi.org/10.3390/genes10080557 |
Ejemplares similares
-
A defective structural zipper in photoreceptors causes inherited blindness
por: Faber, Siebren, et al.
Publicado: (2022) -
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
por: Collin, Gayle B., et al.
Publicado: (2020) -
Gene augmentation of LCA5-associated Leber congenital amaurosis ameliorates bulge region defects of the photoreceptor ciliary axoneme
por: Faber, Siebren, et al.
Publicado: (2023) -
Epigenetic inheritance of proteostasis and ageing
por: Li, Cheryl, et al.
Publicado: (2016) -
Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects
por: Chen, Holly Y, et al.
Publicado: (2023)