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Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex
Binge eating (BE) is a heritable trait associated with eating disorders and involves episodes of rapid, large amounts of food consumption. We previously identified cytoplasmic FMR1-interacting protein 2 (Cyfip2) as a genetic factor underlying compulsive-like BE in mice. CYFIP2 is a homolog of CYFIP1...
Autores principales: | Babbs, Richard K., Beierle, Jacob A., Ruan, Qiu T., Kelliher, Julia C., Chen, Melanie M., Feng, Ashley X., Kirkpatrick, Stacey L., Benitez, Fabiola A., Rodriguez, Fred A., Pierre, Johanne J., Anandakumar, Jeya, Kumar, Vivek, Mulligan, Megan K., Bryant, Camron D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723122/ https://www.ncbi.nlm.nih.gov/pubmed/31324746 http://dx.doi.org/10.1534/g3.119.400470 |
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