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Kinetic Modeling of DUSP Regulation in Herceptin-Resistant HER2-Positive Breast Cancer

Background: HER2 (human epidermal growth factor 2)-positive breast cancer is an aggressive type of breast cancer characterized by the overexpression of the receptor-type protein tyrosine kinase HER2 or amplification of the HER2 gene. It is commonly treated by the drug trastuzumab (Herceptin), but re...

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Detalles Bibliográficos
Autores principales:	Buiga, Petronela, Elson, Ari, Tabernero, Lydia, Schwartz, Jean-Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723192/ https://www.ncbi.nlm.nih.gov/pubmed/31357550 http://dx.doi.org/10.3390/genes10080568

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