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Forced Degradation Studies to Identify Critical Process Parameters for the Purification of Infectious Measles Virus

Oncolytic measles virus (MV) is a promising treatment for cancer but titers of up to 10(11) infectious particles per dose are needed for therapeutic efficacy, which requires an efficient, robust, and scalable production process. MV is highly sensitive to process conditions, and a substantial fractio...

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Detalles Bibliográficos
Autores principales:	Loewe, Daniel, Häussler, Julian, Grein, Tanja A., Dieken, Hauke, Weidner, Tobias, Salzig, Denise, Czermak, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723239/ https://www.ncbi.nlm.nih.gov/pubmed/31394824 http://dx.doi.org/10.3390/v11080725

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