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Correlation between Thiopurine S-Methyltransferase Genotype and Adverse Events in Inflammatory Bowel Disease Patients

Background and Objectives: In patients with inflammatory bowel diseases (IBD), the use of azathioprine results in adverse events at a rate of 5% to 20%. The aim of the study was to assess a possible correlation between genetic variability of the enzyme thiopurine S-methyltransferase (TPMT) and the d...

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Detalles Bibliográficos
Autores principales: Ribaldone, Davide Giuseppe, Adriani, Alessandro, Caviglia, Gian Paolo, De Nicolò, Amedeo, Agnesod, Danilo, Simiele, Marco, Riganò, Danila, Pellicano, Rinaldo, Canaparo, Roberto, Di Perri, Giovanni, D’Avolio, Antonio, Luzza, Francesco, Abenavoli, Ludovico, Saracco, Giorgio Maria, Astegiano, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723288/
https://www.ncbi.nlm.nih.gov/pubmed/31387318
http://dx.doi.org/10.3390/medicina55080441

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