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Correlation between Thiopurine S-Methyltransferase Genotype and Adverse Events in Inflammatory Bowel Disease Patients
Background and Objectives: In patients with inflammatory bowel diseases (IBD), the use of azathioprine results in adverse events at a rate of 5% to 20%. The aim of the study was to assess a possible correlation between genetic variability of the enzyme thiopurine S-methyltransferase (TPMT) and the d...
Autores principales: | Ribaldone, Davide Giuseppe, Adriani, Alessandro, Caviglia, Gian Paolo, De Nicolò, Amedeo, Agnesod, Danilo, Simiele, Marco, Riganò, Danila, Pellicano, Rinaldo, Canaparo, Roberto, Di Perri, Giovanni, D’Avolio, Antonio, Luzza, Francesco, Abenavoli, Ludovico, Saracco, Giorgio Maria, Astegiano, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723288/ https://www.ncbi.nlm.nih.gov/pubmed/31387318 http://dx.doi.org/10.3390/medicina55080441 |
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