Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers

The disaccharide trehalose is an autophagy inducer, but its pharmacological application is severely limited by its poor pharmacokinetics properties. Thus, trehalose was coupled via suitable spacers with squalene (in 1:2 and 1:1 stoichiometry) and with betulinic acid (1:2 stoichiometry), in order to...

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Detalles Bibliográficos
Autores principales: Colombo, Eleonora, Biocotino, Michele, Frapporti, Giulia, Randazzo, Pietro, Christodoulou, Michael S., Piccoli, Giovanni, Polito, Laura, Seneci, Pierfausto, Passarella, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723367/
https://www.ncbi.nlm.nih.gov/pubmed/31434235
http://dx.doi.org/10.3390/pharmaceutics11080422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723367/
https://www.ncbi.nlm.nih.gov/pubmed/31434235
http://dx.doi.org/10.3390/pharmaceutics11080422

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