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Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers
The disaccharide trehalose is an autophagy inducer, but its pharmacological application is severely limited by its poor pharmacokinetics properties. Thus, trehalose was coupled via suitable spacers with squalene (in 1:2 and 1:1 stoichiometry) and with betulinic acid (1:2 stoichiometry), in order to...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723367/ https://www.ncbi.nlm.nih.gov/pubmed/31434235 http://dx.doi.org/10.3390/pharmaceutics11080422 |