A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges

Mechanobiology studies from the last decades have brought significant insights into many domains of biological research, from development to cellular signaling. However, mechano-regulation of subcellular components, especially membranous organelles, are only beginning to be unraveled. In this paper,...

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Detalles Bibliográficos
Autores principales: Feng, Qian, Lee, Sung Sik, Kornmann, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723503/
https://www.ncbi.nlm.nih.gov/pubmed/31426349
http://dx.doi.org/10.3390/mi10080538
Descripción
Sumario:Mechanobiology studies from the last decades have brought significant insights into many domains of biological research, from development to cellular signaling. However, mechano-regulation of subcellular components, especially membranous organelles, are only beginning to be unraveled. In this paper, we take mitochondrial mechanobiology as an example to discuss recent advances and current technical challenges in this field. In addition, we discuss the needs for future toolbox development for mechanobiological research of intracellular organelles.

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