A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges

Mechanobiology studies from the last decades have brought significant insights into many domains of biological research, from development to cellular signaling. However, mechano-regulation of subcellular components, especially membranous organelles, are only beginning to be unraveled. In this paper,...

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Detalles Bibliográficos
Autores principales: Feng, Qian, Lee, Sung Sik, Kornmann, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723503/
https://www.ncbi.nlm.nih.gov/pubmed/31426349
http://dx.doi.org/10.3390/mi10080538
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author Feng, Qian
Lee, Sung Sik
Kornmann, Benoît
author_facet Feng, Qian
Lee, Sung Sik
Kornmann, Benoît
author_sort Feng, Qian
collection PubMed
description Mechanobiology studies from the last decades have brought significant insights into many domains of biological research, from development to cellular signaling. However, mechano-regulation of subcellular components, especially membranous organelles, are only beginning to be unraveled. In this paper, we take mitochondrial mechanobiology as an example to discuss recent advances and current technical challenges in this field. In addition, we discuss the needs for future toolbox development for mechanobiological research of intracellular organelles.
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spelling pubmed-67235032019-09-10 A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges Feng, Qian Lee, Sung Sik Kornmann, Benoît Micromachines (Basel) Communication Mechanobiology studies from the last decades have brought significant insights into many domains of biological research, from development to cellular signaling. However, mechano-regulation of subcellular components, especially membranous organelles, are only beginning to be unraveled. In this paper, we take mitochondrial mechanobiology as an example to discuss recent advances and current technical challenges in this field. In addition, we discuss the needs for future toolbox development for mechanobiological research of intracellular organelles. MDPI 2019-08-16 /pmc/articles/PMC6723503/ /pubmed/31426349 http://dx.doi.org/10.3390/mi10080538 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Feng, Qian
Lee, Sung Sik
Kornmann, Benoît
A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges
title A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges
title_full A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges
title_fullStr A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges
title_full_unstemmed A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges
title_short A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges
title_sort toolbox for organelle mechanobiology research—current needs and challenges
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723503/
https://www.ncbi.nlm.nih.gov/pubmed/31426349
http://dx.doi.org/10.3390/mi10080538
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