APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer’s Disease Risk in a Multiracial Sample

Variants in the APOE gene region may explain ethnic differences in the association of Alzheimer’s disease (AD) with ε4. Ethnic differences in allele frequencies for three APOE region SNPs (single nucleotide polymorphisms) were identified and tested for association in 19,398 East Asians (EastA), incl...

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Autores principales: Choi, Kyu Yeong, Lee, Jang Jae, Gunasekaran, Tamil Iniyan, Kang, Sarang, Lee, Wooje, Jeong, Jangho, Lim, Ho Jae, Zhang, Xiaoling, Zhu, Congcong, Won, So-Yoon, Choi, Yu Yong, Seo, Eun Hyun, Lee, Seok Cheol, Gim, Jungsoo, Chung, Ji Yeon, Chong, Ari, Byun, Min Soo, Seo, Sujin, Ko, Pan-Woo, Han, Ji-Won, McLean, Catriona, Farrell, John, Lunetta, Kathryn L., Miyashita, Akinori, Hara, Norikazu, Won, Sungho, Choi, Seong-Min, Ha, Jung-Min, Jeong, Jee Hyang, Kuwano, Ryozo, Song, Min Kyung, An, Seong Soo A., Lee, Young Min, Park, Kyung Won, Lee, Ho-Won, Choi, Seong Hye, Rhee, Sangmyung, Song, Woo Keun, Lee, Jung Sup, Mayeux, Richard, Haines, Jonathan L., Pericak-Vance, Margaret A., Choo, IL Han, Nho, Kwangsik, Kim, Ki-Woong, Lee, Dong Young, Kim, SangYun, Kim, Byeong C., Kim, Hoowon, Jun, Gyungah R., Schellenberg, Gerard D., Ikeuchi, Takeshi, Farrer, Lindsay A., Lee, Kun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723529/
https://www.ncbi.nlm.nih.gov/pubmed/31426376
http://dx.doi.org/10.3390/jcm8081236

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